ABSTRACT
Background and aim: Due to significant role of air pollutants on lung diseases this study aimed to examine the effects of concentration of air pollutants [CO¡SO[2]¡NO[2]] on Spirometric lung function
Methods: The sample cities, Arak [as an industrial contaminated city] and Khomain, [as a non-contaminated non-industrial city], were divided into Ira 10 and 5 regions, respectively. A sample of air pollutants [CO¡SO[2]¡NO[2]] was measured randomly by PSI [Pollution Standard Index] machine throughout the year from spring to winter. Random samples consisted of 522 non-smokers from Khomain and 547 from Arak were selected. Pulmonary function tests were completed on all participants. The mean concentration of air pollutants and distribution index of lung capacity were subjected to regression analysis
Results: Analysis of the results showed that PSI in Arak was 101.83+/-4.54 and in Khomain was 89.17+/-18.58 [P<0.05]. Measured values FVC and PEF in Arak were significant lower than Khomain [P<0.05]. The mean values for the concentration of CO, SO[2] and NO[2] in Arak were higher than Khomain, although the differences were significant only for CO and SO[2] [P<0.001]. The three pollutants [NO[2], SO[2] and CO] showed a significant correlation between mean VC [P<0. 001] FVC, [P<0.05] with concentrations of SO[2] and PEF with NO[2] [P<0.001]. In Arak, the correlation between the predicted FVC and concentration of CO was negative and significant
Conclusion: The mean value of concentration of SO[2], CO and NO[2] in Arak were higher than Khomain. In Arak, a significant negative correlation was also observed between FVC and the concentration of CO. These pollutants and their resources should be annually measured and monitored
ABSTRACT
Background: The present study investigates the effect of different concentrations of air pollutants [PM10, O3. H[2]S] on the function of lung
Materials and Methods: Arak and Khomain cities were divided into 10 and 5 regions, respectively. A sample of air pollutants [PM10, O3 .H[2]S] was measured by PSI [pollution standard index] machine randomly from spring to winter. Two random samples consisting of 1069 non-smoker residents of the two cities [522 from Khomain and 547 from Arak] were selected. Regression test mode were used to analyze data
Results: PSI in the cities Arak and Khomain was 101.83+/-14.54 and 89.17+/-18.58, respectively. Predicted values of FVC, FEVI, FEF 25-75%, MEF 50%, and PEF in Arak were 10.2%, 11.7%, 35.5%, 30.9%, and 40% abnormal, respectively. These values in Khomain were 8.8%, 11.3%, 35.4%, 33.9%, and 40.6% abnormal, respectively. The concentrations of H[2]S in both cities were above the standard values. There was no significant relationship between the concentrations of O3, H[2]S, PM10 and vital capacity. However, there was a considerable correlation between the mean of FEF, FEF 25- 75%, and concentration of O3 at P<0.001 and P=0.016 level of significance, respectively. In Arak the correlation observed between FVC and concentration of O3 was not significant. In Khomain a negative correlation was observed between VC with H[2]S and PM10 on one hand and FVC with H[2]S and PM10 on the other
Conclusion: The main pollutants in Arak was PM10 and in Khomain were H[2]S and O3. Measuring these pollutants throughout the year is necessary
ABSTRACT
Homocysteinernia is currently regarded as an independent risk factor in venous thrombosis and vascular diseases. So noticing its causes and risk factors in high risk populations, such as elderly and chronically ill patients is of much importance. This research is designed, considering the important role of homocysteinemia and the lack of statistics and adequate information about the prevalence of this disease among hospitalized patients in ICU. The is a descriptive, cross-sectional study, done by census sampling method on patients admitted in ICU of Rasoul-Akram hospital, during a 6 months period. Epidemiologic data was collected from the patients' files. A blood sample was taken from the patient to measure homocysteine level. Data was introduced using descriptive statistics. 52 patients with the mean age of 58.42 were included in this study. Among these, 12 [23.1%] had a high homocysteine level and the other 40 patients [76.9%] had a normal range of homocysteine. The mean homocysteine level in patients with normal levels was 9.28 [3.08-15.48] micromol/dl and the mean in patients with homocysteinemia was 21.05 [11.05-31.05]. Among patients with homocysteinemia, 25% had renal failure and 25% were presented with cerebrovascular accident [CVA]. There was no significant difference between homocystein level in patients with renal failure and those with CVA. According to the 23.1% frequency of hyperhomocysteinemia in hospitalized patients of our study, also considering the Folate and vitamin B6 and B12 role in homocysteinemia, and also due to previous epidemiologic studies, it seems that evaluating Folate, vitamin B6 and B 12, creatinine clearance and plasma albumin level may clarify the role of these factors as the probable predictive factor in patients with homocysteinemia